Table 3. Multiple linear regression model (backward stepwise elimination using bootstrapping) of relative weight loss with baseline variables.
| Variable | B | 95%CI | 95%CI | R2 | p |
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Fasting glucose (mmol/l) | -0.332 | -0.485 | -0.180 | 0.078 | 0.001 |
| Insulin dose (IU) | 0.010 | 0.002 | 0.018 | 0.032 | 0.014 |
| Waist-to-hip ratio | 6.790 | 2.096 | 11.775 | 0.025 | 0.003 |
| Numbness in extremities | 1.860 | 0.853 | 2.874 | 0.065 | 0.002 |
| Anxiety (HADS) | -0.219 | -0.344 | -0.111 | 0.056 | 0.001 |
Explained variance in this model R2 = 0.25, F(5) = 12.54, p<0.001; C-index = 0.74. Variables entered into the model: age; sex; weight; waist-to-hip ratio; fasting glucose; total daily insulin dose; total daily metformin dose; physical complaints related to diabetes (polyuria, pruritus, eye problems, numbness in extremities, all yes/no); exercise (days per week ≥30 minutes of exercise); history of weight loss dieting (number of different diets); fatigue (Checklist Individual Strength); depression and anxiety (Hospital Anxiety and Depression scale); quality of life (EQ-5D VAS score); self-esteem (Rosenberg self-esteem); eating disorders (EDE-Q); and binge eating disorder (DSM-V criteria, yes/no).