Table 2.

Comparison of DNA methylation (%) between spontaneous preterm cases and term controls at entry to care^*.

Gene symbol	Cases (n=23)	Controls (n=19)	p-value
ABCB1	16.98 ± 6.14	16.25 ± 6.96	0.938
APC	5.56 ± 4.67	11.47 ± 5.15	0.407
ATM	12.49 ± 5.64	13.30 ± 6.40	0.926
BMP6	9.58 ± 5.58	19.12 ± 6.15	0.264
CAV1	3.28 ± 4.31	11.07 ± 4.89	0.246
CADM1	18.30 ± 7.02	26.15 ± 7.96	0.470
CDKN1B	6.09 ± 4.72	12.84 ± 5.35	0.356
CDKN2B	6.59 ± 6.20	20.69 ± 6.84	0.140
CHFR	5.19 ± 5.48	20.24 ± 6.04	0.077
CST6	77.00 ± 3.58	83.47 ± 3.94	0.238
DAB2IP	5.01 ± 4.95	20.51 ± 5.46	0.045
DAPK1	13.39 ± 5.84	19.35 ± 6.44	0.502
DSC3	8.01 ± 6.83	12.53 ± 7.51	0.670
EPB41L3	16.10 ± 6.42	20.43 ± 7.12	0.658
FHIT	11.91 ± 6.57	19.60 ± 7.09	0.438
GADD45A	8.03 ± 5.58	18.46 ± 6.15	0.222
GPC3	45.96 ± 4.77	49.35 ± 5.26	0.640
HOXA5	7.77 ± 5.61	20.67 ± 6.19	0.136
HOXD11	39.30 ± 8.04	30.62 ± 8.66	0.472
BRCA2	30.21 ± 8.09	43.66 ± 8.77	0.277
CALCA	30.06 ± 4.81	26.42 ± 5.32	0.618
CDX2	13.88 ± 5.37	17.53 ± 6.09	0.660
CXCL12	8.56 ± 5.44	21.53 ± 5.97	0.122
CYP1B1	61.33 ± 6.82	59.53 ± 6.82	0.858

^*Data are means ± SE.

Models were adjusted for age, BMI, parity, ethnicity and cigarette smoking.