Table 3.

Comparison of DNA methylation (%) between spontaneous preterm delivery cases and controls during the 3^rd trimester^*.

Gene symbol	Cases (n=23)	Controls (n=19)	p-value
ABCB1	6.31 ± 7.84	33.85 ± 8.27	0.024
APC	0.63 ± 6.41	30.27 ± 7.11	0.005
ATM	6.85 ± 6.92	28.70 ± 7.67	0.045
BMP6	4.95 ± 5.87	33.45 ± 6.47	0.003
CAV1	4.78 ± 6.35	27.68 ± 7.00	0.022
CADM1	5.63 ± 6.10	25.60 ± 6.61	0.064
CDKN1B	5.98 ± 6.96	36.65 ± 8.26	0.009
CDKN2B	9.08 ± 7.20	27.28 ± 7.94	0.103
CHFR	5.56 ± 6.93	34.52 ± 7.65	0.009
CST6	77.36 ± 4.11	84.63 ± 4.66	0.253
DAB2IP	8.44 ± 6.75	23.12 ± 7.27	0.154
DAPK1	13.12 ± 8.02	46.57 ± 8.02	0.007
DSC3	12.35 ± 8.67	25.86 ± 9.76	0.327
EPB41L3	2.61 ± 5.66	23.03 ± 6.41	0.024
FHIT	7.39 ± 7.42	31.28 ± 8.00	0.037
GADD45A	10.13 ± 7.35	34.00 ± 7.93	0.036
GPC3	47.62 ± 5.35	61.83 ± 5.77	0.084
HOXA5	2.32 ± 5.90	25.31 ± 6.36	0.013
HOXD11	19.17 ± 7.65	33.54 ± 8.96	0.243
BRCA2	32.96 ± 8.40	31.99 ± 9.45	0.941
CALCA	20.00 ± 5.56	39.76 ± 6.17	0.025
CDX2	14.28 ± 7.41	29.28 ± 8.20	0.187
CXCL12	11.53 ± 7.52	40.15 ± 8.11	0.016
CYP1B1	45.53 ± 9.67	76.05 ± 10.09	0.036

^*Data are means ± SE.

Models were adjusted for age, BMI, parity, ethnicity and cigarette smoking.