. Author manuscript; available in PMC: 2017 Sep 1.

Published in final edited form as: Behav Genet. 2016 Apr 16;46(5):693–704. doi: 10.1007/s10519-016-9792-4

Table III.

Results of association analyses with low frequency genetic variants in CHRN genes and antisocial drug dependence in all subjects in Sample 1.

Gene	Num of Low Frequency Variants	SKAT-O p-value	C-alpha p-value
CHRNA1	96	1	0.93
CHRNA2	81	0.59	0.47
CHRNA5/CHRNA3/CHRNB4	217	0.64	0.81
CHRNA4	63	0.89	0.67
CHRNA6/CHRNB3	243	0.93	0.83
CHRNA7	384	0.90	0.88
CHRNA9	83	0.44	0.54
CHRNA10	47	0.10	0.25
CHRNB1	30	0.21	0.11
CHRNB2	52	0.41	0.62
CHRNE	51	1	0.64
CHRND/CHRNG	62	0.47	0.46