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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Mol Cancer Ther. 2016 May 27;15(8):1809–1822. doi: 10.1158/1535-7163.MCT-15-0688

Table 2.

Analysis of drug interactions using Chou Talalay method.

Analysis Chou and Talalay Syn II < 1, Add II = 1, Ant II > 1

Drugs/nm Estimated 95%, CI Conclusion:
Eribulin=1, MLN =50 0.538 (0.334, 0.741) Synergy
Eribulin=3, MLN =100 0.481 (0.329, 0.641) Synergy
Eribulin=5, MLN =100 0.645 (0.501, 0.852) Synergy
Eribulin=3, MLN =150 0.341 (0.247, 0.777) Synergy