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Isolated mitochondria from the hippocampus of Cr+/y and Crt−/y mice show similar oxygen consumption when equal numbers of mitochondria are examined. (A) Oxygen consumption was examined in isolated mitochondria the presence of malate and pyruvate. No differences were observed between groups. (B) Complex II activity was assessed by incubating mitochondria with rotenone and succinate prior to respirometry. Values are mean +/− SEM, n=4 with each sample run in duplicate.
