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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Fertil Steril. 2016 May 10;106(2):363–370.e3. doi: 10.1016/j.fertnstert.2016.04.023

Table 2.

Evaluating association of variables with adverse placental outcomes by GEE model. Adjust model accounted for estradiol, ICSI, age, and male factor infertility.

Variable Unadjusted Odds Ratio
(95%CI)
P value Adjusted Odds Ratio
(95%CI)
P value
Estradiol on hCG 1.36 (1.13–1.65) 0.001 1.32 (1.13–1.52) 0.001
ICSI 3.86 (1.61–9.27) 0.002 4.21 (1.73–10.25) 0.002
Female Age 1.00 (0.99–1.01) 0.37 1.03 (0.96–1.10) 0.34
Male Factor 1.27 (0.73–2.20) 0.38 1.30 (0.70–2.23) 0.40
BMI 1.02 (0.96–1.10) .43
Days of Stimulation 0.95 (0.81–1.11) 0.35
Gonadotropins used 0.99 (0.98–1.01) 0.33
Follicles 1.01 (0.98–1.05) 0.39
Oocytes Retrieved 1.02 (0.98–1.06) 0.22
Mature Oocytes 1.04 (0.99–1.09) 0.07
Assisted Hatching 2.22 (0.28–17.58) 0.45
Blastocyst Transfer 1.21 (0.70–2.09) 0.47
Embryos transferred 0.99 (0.93–1.05) 0.82