FIG. 3.

Secretion of IL-8 from MKN45 cells cocultured with the two different H. pylori types, RpoB^Thr (n = 20) and RpoB^Ala (n = 20). All the H. pylori strains were cagA positive (East Asian-type CagA). The amounts of IL-8 protein excreted by the cells was measured by enzyme-linked immunosorbent assay. The levels of IL-8 secreted by RpoB^Thr-type infected cells were found to be significantly higher (P < 0.05 by the Mann-Whitney rank sum test) than the levels secreted by RpoB^Ala-type infected cells.