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. 2016 Aug 5;17:560. doi: 10.1186/s12864-016-2842-8

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Validation of dyscooperated IRF8 in LUAD and LUSC. a Cooperativity alterations between TF pairs that highly coordinated in normal/tumor. b Highly dyscooperated TFs also identified in the previous NSCLC dataset. c Comparison of expression alteration between IRF8’s target and non-target genes