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. Author manuscript; available in PMC: 2016 Aug 6.
Published in final edited form as: Head Neck. 2015 Jun 16;38(2):237–246. doi: 10.1002/hed.23877

Figure 3.

Figure 3

Intratumoral injection of GLV-1h68 in silk-elastin-like protein polymer (SELP) into flank tumors results in equivalent tumor volume regression as compared to GLV-1h68 in phosphate-buffered saline (PBS). A single intratumoral injection of GLV-1h68, in either SELP or PBS, as delivered into 8505c murine flank tumors. At day 10 and later, viral transgene expression was enhanced by SELP over PBS, as measured by green fluorescent protein (GFP; n = 3 per group) (A) and luciferase (n = 5 per group) (C) quantification. Representative animals were imaged for GFP (B) or luciferase (D). Tumor volumes were measured and demonstrate equivalent, near-complete, tumor regression for GLV-1h68 in both PBS and SELP (n = 8 per group) (E). [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]