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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Free Radic Biol Med. 2016 May 14;98:103–112. doi: 10.1016/j.freeradbiomed.2016.05.010

Figure 2. Schematic diagram of macroautophagy.

Figure 2

Macroautophagy involves the formation of distinct complexes during five sequential stages: (1) initiation, (2) expansion and elongation, (3) closure, (4) maturation and fusion of autophagosomes with lysosomes, and (5) degradation of the autophagic cargo. See text for details.