Table 1. Grouping of HLA-I allotypes by predicted binding motif.
| Group | A1 | A2 | A3 | A24 | A26 | B7 | B8 | B27 | B39 | B44 | B58 | B62 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Allotype | HLA-A*01:01 | HLA-A*02:01 | HLA-A*03:01 | HLA-A*23:01 | HLA-A*25:01 | HLA-B*07:02 | HLA-B*08:01 | HLA-B*27:02 | HLA-B*15:09 | HLA-B*18:01 | HLA-B*15:17 | HLA-B*15:01 |
| HLA-A*29:02 | HLA-A*02:03 | HLA-A*11:01 | HLA-A*24:02 | HLA-A*26:01 | HLA-B*35:01 | HLA-B*08:02 | HLA-B*27:03 | HLA-B*15:10 | HLA-B*40:01 | HLA-B*57:01 | HLA-B*15:02 | |
| HLA-A*30:02 | HLA-A*02:10 | HLA-A*30:01 | HLA-A*24:03 | HLA-A*26:02 | HLA-B*35:03 | HLA-B*08:03 | HLA-B*27:05 | HLA-B*38:01 | HLA-B*40:13 | HLA-B*57:02 | HLA-B*15:42 | |
| HLA-A*43:01 | HLA-A*02:11 | HLA-A*31:01 | HLA-A*24:07 | HLA-A*26:03 | HLA-B*39:10 | HLA-B*14:01 | HLA-B*27:20 | HLA-B*39:01 | HLA-B*41:01 | HLA-B*57:03 | HLA-B*46:01 | |
| HLA-A*80:01 | HLA-A*02:12 | HLA-A*33:03 | HLA-A*24:19 | HLA-A*66:01 | HLA-B*42:01 | HLA-B*14:02 | HLA-B*39:02 | HLA-B*44:05 | HLA-B*58:01 | |||
| HLA-A*02:16 | HLA-A*68:01 | HLA-A*32:07 | HLA-A*68:23 | HLA-B*42:02 | HLA-B*39:06 | HLA-B*45:01 | ||||||
| HLA-A*02:19 | HLA-A*74:01 | HLA-B*51:01 | HLA-B*48:01 | |||||||||
| HLA-A*02:50 | HLA-B*54:01 | |||||||||||
| HLA-A*03:19 | HLA-B*55:01 | |||||||||||
| HLA-B*56:01 | ||||||||||||
| HLA-B*81:01 | ||||||||||||
| HLA-B*83:01 |
pMHC-I binding was predicted using the NetMHCpan-2.8 prediction algorithm for 76 MHC-I allotypes, which were subsequently grouped according to overlapping binding motifs resulting in 12 groups. Binding data for the 6 allotypes denoted in italic in table 1 were inconclusive (for details see text).