Table 1.
Baseline characteristics of participants in the Harvard Aging Brain Study (n=280).
| Characteristic | Mean (Range) |
|---|---|
|
| |
| Age | 73.7 (62.5–90 years) |
|
| |
| Sex | Females 58.8% (n=164) |
| Males 41.2% (n=116) | |
|
| |
| Years of Education | 15.8 (6–20 years) |
|
| |
| Clinical Dementia Rating global score | 0 |
|
| |
| Mini-Mental State Exam | 29 (25–30) |
|
| |
| APOE4 Carriers | 28.9% |
|
| |
| Body-Mass Index | 26.9 (16–41) |
| - Underweight (BMI<18.5) | 2.5% (n=7) |
| - Normal (BMI 18.5–24.9) | 31.8% (n=89) |
| - Overweight (BMI 25–29.9) | 41.4% (n=116) |
| - Obese (BMI>30) | 24.3% (n=68) |
|
| |
| Statin Use | 43.6% |
|
| |
| Antihypertensive Use | 58.2% |
|
| |
| Smoking | 4.3% |
|
| |
| Diabetes mellitus | 8.8% |
|
| |
| Cortical PiB retention (DVR) | 1.17 (0.95–1.82) |
APOE4 (apolipoprotein ɛ4), BMI (body-mass index), DVR (distribution volume ratio), PiB (Pittsburgh Compound B).