Table 2.
Secondary analyses of BMI and PiB retention.
| Dependent Variable: PiB PET | β | P-value | |
|---|---|---|---|
| Model 1* | Normal: BMI | −0.253 | 0.01 |
| Overweight: BMI | −0.154 | 0.08 | |
| Obese: BMI | −0.098 | 0.47 | |
| Model 2 | APOE4 carrier: BMI | −0.267 | 0.02 |
| APOE4 non-carrier: BMI | −0.074 | 0.33 | |
| Model 3 | BMI | −0.054 | 0.45 |
| APOE4 carrier | 0.381 | <0.001 | |
| BMI × APOE4 interaction term | −0.142 | 0.04 | |
All models are adjusted for age, sex, and years of education.
Model 1 is also adjusted for APOE4 carrier status.
APOE4 (apolipoprotein ɛ4), BMI (body-mass index), PET (positron emission tomography), PiB (Pittsburgh Compound B).