Figure 5. Transgenic Bcl2 expression and p53 deficiency partially rescue the early stages of T-cell development in ScanT mice.
a) FACs analysis of lineage negative thymocytes in the indicated strains showing the percentage of CD44hicKithi thymocytes. b) Analysis of ETP and DN2 proportions in cells gated in (a). c) Analysis of DN3 (CD25+CD44−) and DN4 (CD25−CD44−) proportion in the indicated strains. d) Quantitation of cell numbers at different developmental stages in the indicated strains. (Mean ± SD). Data is representative of more than 4 independent experiments.