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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Vascul Pharmacol. 2016 May 31;84:47–54. doi: 10.1016/j.vph.2016.05.015

Figure 4. SII does not potentiate PGE2-mediated contraction.

Figure 4

(A) Representative wire myography trace showing that 10 minute pre-treatment with 30 μM SII did not potentiate 100 nM PGE2-mediated contraction. (B) Representative trace of arterial rings preincubated with 30 μM SII for 10 minutes, followed by priming with 1 nM Ang II and addition of 100 nM PGE2. (C) Quantification of SII results, showing a lack of potentiation by SII on PGE2-induced contraction (3rd bar from left), and SII blockade of PGE2-mediated contraction of Ang II-primed vessels (4th bar from left) (N = 5).