Figure 7. GPI-anchored glycosylated prion protein in raft-like membranes.
Prion protein, N-glycan 1, N-glycan 2, GPI-anchor, cholesterol, POPC (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine), and PSM (N-palmitoyl sphingomyelin) are represented in cartoon (HA: orange, HB: blue, HC: red), green surface, blue surface, magenta sticks, light green spheres, light blue spheres, and light yellow spheres, respectively. The bilayer composition is about 1 : 1 : 1 of cholesterol : POPC : PSM. Water molecules and KCl ions are omitted for clarity.