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. Author manuscript; available in PMC: 2017 Aug 15.
Published in final edited form as: J Immunol. 2016 Jul 15;197(4):1335–1342. doi: 10.4049/jimmunol.1502669

FIGURE 4.

FIGURE 4

Supernatants of ILC2s promote B cell Ig production. Lung ILC2s and splenic B cells were isolated from BALB/c mice. B cells were cultured with or without pooled supernatants (sup) of ILC2s in the presence or absence of anti-CD40 antibody (1.5 μg/ml) plus IL-4 (10 ng/ml) for 4 days. Ig concentrations in the culture supernatants were analyzed by ELISA. Data (mean±SEM, n=3) are representative of three independent experiments. *, p<0.05; **, p<0.01 compared to cells cultured in the absence of ILC2 supernatants.