Skip to main content
. Author manuscript; available in PMC: 2017 Aug 15.
Published in final edited form as: J Immunol. 2016 Jul 15;197(4):1343–1352. doi: 10.4049/jimmunol.1502357

Figure 1.

Figure 1

Schematic for TLR9 constructs. Full-length TLR9 has 26 leucine rich repeats, a transmembrane domain and a C-terminus containing the Toll-IL-1 resistance domain. TLR9 is proteolytically cleaved between LRR14 and LRR15 resulting in TLR9471-1032 and TLR91-440. We have generated two additional forms. One form includes the hinge region (aa 441-470) in the C-terminal proteolytic cleavage product (TLR9441-1032 ) and the other includes the hinge region on the N-terminal cleavage product (TLR91-471).