TABLE 4.
Histopathology analysis of specimens (stomach, liver, and small intestine tissue) from mice colonized with H. hepaticus or H. typhlonius, as well as Helicobacter-negative tissue specimens, determined by PCR-DGGE
| AH | Strain | Tissue (no. of specimens) | Helicobacter sp. detected | Histo- pathology |
|---|---|---|---|---|
| 2 | SPF-SCID | Liver (4) | H. typhlonius | Normal |
| 2 | B6sJl | Liver (1) | H. typhlonius | Normal |
| 2 | SPF-SCID | Liver (1) | Negative | Normal |
| 2 | SPF-SCID | Stomach (1) | H. typhlonius | Normal |
| 2 | SPF-SCID | Stomach (1) | Negative | Normal |
| 2 | SPF-SCID | Intestine (1) | H. typhlonius | Normal |
| 3 | ApoE−/− | Liver (1) | H. hepaticus | Hepatitis |
| 3 | ApoE−/− | Liver (2) | Negative | Normal |
| 3 | ApoE−/− | Stomach (1) | H. hepaticus | Normal |
| 3 | ApoE−/− | Intestine (1) | Negative | Normal |
| 3 | C57BL/6 | Stomach (3) | H. typhlonius | Gastritis |
| 3 | C57BL/6 | Intestine (1) | H. typhlonius | Normal |
| 3 | BALB/cA | Liver (3) | H. hepaticus | Hepatitis |
| 3 | BALB/cA | Liver (2) | Negative | Normal |
| 3 | BALB/cA | Stomach (5) | H. hepaticus | Normal |
| 4 | IL-10−/− | Liver (1) | Negative | Abscess |
| 4 | IL-10−/− | Stomach (1) | Negative | Crypt abscess |