Table 4.

Parameter estimates and their standard errors using Taylor linearization methods

	Piecewise-Poisson regression			Cox regression
	Estimate	Standard error	P-value	Estimate	Standard error	P-value
Age (years)
α1 [55–75)	−6.318	1.627	<0.001
α2 [75–80)	−5.914	1.598	<0.001
α3 [80–85]	−5.219	1.636	0.001
LogIGF1	−0.160	0.317	0.614	−0.235	0.320	0.464
BMI (kg/m2)
Overweight (25–30)	0.225	0.286	0.431	0.167	0.285	0.557
Obese (≥30)	0.571	0.327	0.081	0.439	0.319	0.169
Smoking status
Current smokers	−0.096	0.417	0.817	−0.186	0.418	0.657
Former smokers	0.013	0.242	0.957	−0.008	0.240	0.972
Family history	−0.261	0.409	0.524	−0.368	0.466	0.407
Diabetes	−0.381	0.450	0.397	−0.386	0.424	0.385
D’Amico score
Medium	0.858	0.361	0.017	0.927	0.349	0.008
High	2.191	0.327	0.000	2.242	0.313	0.000
Very high/metastatic	4.262	0.366	0.000	4.346	0.326	0.000