Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Table of PI3K, AKT, and mTOR inhibitors in development [4].
| PI3K/AKT/mTOR pathway inhibitors | ||
|---|---|---|
| PI3K | AKT | mTOR |
| AZD6482 | A-443654 | AZD-8055 |
| AR245408 (XL 147) | AR-42 | BGT226 |
| BAY 80-6946 | AR-67 (DB-67) | Everolimus |
| BKM120 | AZD5363 | INK-128 |
| BYL719 | GSK690693 | NVP-BEZ235 |
| GDC-0941 | KP372-1 | ONC-01910 |
| GDC-0980 | MK-2206 | OSI-027 |
| GSK2636771 | SR13668 | PP-242 |
| PF-04691502 | Triciribine (API-2) | Rapamycin (sirolimus) |
| PX-866 | VIII | Ridaforolimus |
| ONC-01910 | VQD-002 (API-2) | Temsirolimus |
| WYE-354 | ||
