TABLE 2.
Description of deletions from M. africanuma
| Deleted sequence | Start | End | Length (bp) | Affected ORF(s) | Rearranged sequence |
|---|---|---|---|---|---|
| RD720 | 76527 | 84934 | 8,408 | Rv0069c-Rv0075 | |
| RD721 | 82923 | 84589 | 1,667 | Rv0074-Rv0075 | |
| RD701 | 149241 | 150980 | 1,740 | Rv0124 | |
| RD702 | 216795 | 218516 | 1,722 | Rv0186 | 217874-217522 |
| RD722 | 1041193 | 1049812 | 8,620 | Rv0933-Rv0939 | |
| RD711 | 1501713 | 1503655 | 1,943 | Rv1333-Rv1336 | |
| RD742 | 1875726 | 1881660 | 5,935 | Rv1661 | 1881507-1881653, 1881484-1881415, 1875861-1875824 |
| RD713 | 2219419 | 2223186 | 3,768 | Rv1977-Rv1979c | 2,319 bp* |
| RD743 | 2235804 | 2239118 | 3,315 | Rv1992c-Rv1996 | |
| RD724 | 2265112 | 2266239 | 1,128 | Rv2018-Rv2019 | Insertion element IS6110 |
| RD728 | 2629497 | 2634359 | 4,863 | Rv2350c-Rv2352c | Insertion element IS6110 |
| RD715 | 2784617 | 2785969 | 1,353 | Rv2479c-Rv2480c | |
| RD727 | 2902567 | 2904318 | 1,752 | Rv2578c-Rv2579 | 29024360-29024396, 2910537-2910595 |
| RD735 | 3781988 | 3782408 | 421 | Rv3370c |
a
The start and end points, length, and affected open reading frames (ORFs) are listed for each region deleted (RD) from M. africanum relative to M. tuberculosis H37Rv. The final column lists any DNA sequence rearranged at the RD junction. The asterisk * indicates that 2,319 bp of sequence from M. tuberculosis strain 210 (http://www.tigr.org/), itself absent from the H37Rv referent, is inverted at the junction of RD713. Deletions are ordered in terms of their locations within the H37Rv genome.