Table 1.
Main demographic, somatometric and clinical characteristics in the whole study population and in patients as divided according to alkaline phosphatase quartiles.
| Whole group (n = 993) | Alk-Phos < median value (n = 497) | Alk-Phos > median value (n = 496) | P for linear trend | |
|---|---|---|---|---|
| Age (years) | 65 ± 14 | 65 ± 14 | 65 ± 13 | 0.93 |
| BMI (kg/m2) | 25 ± 5 | 25 ± 5 | 25 ± 5 | 0.74 |
| Male sex n. (%) | 624 (63) | 343 (69) | 281 (57) | <0.001 |
| Current smokers n. (%) | 149 (15) | 78 (16) | 71 (14) | 0.54 |
| Past smokers n. (%) | 370 (37) | 202 (41) | 168 (34) | 0.03 |
| Diabetics n. (%) | 272 (28) | 127 (26) | 145 (30) | 0.14 |
| On antihypertensive treatment n. (%) | 634 (64) | 320 (64) | 314 (63) | 0.72 |
| Dialysis vintage (months) | 45 (21–85) | 38 (19–76) | 52 (26–96) | <0.001 |
| With cardiovascular comorbidities∗ n. (%) | 533 (54) | 257 (52) | 276 (56) | 0.21 |
|
| ||||
| Systolic blood pressure (mmHg) | 135 ± 22 | 135 ± 22 | 135 ± 23 | 0.99 |
| Diastolic blood pressure (mmHg) | 74 ± 12 | 74 ± 12 | 73 ± 11 | 0.09 |
| Pulse pressure (mmHg) | 74 ± 11 | 73 ± 10 | 74 ± 11 | 0.13 |
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| Cholesterol (mg/dL) | 156 ± 40 | 155 ± 39 | 156 ± 41 | 0.61 |
| Haemoglobin (g/dL) | 11.3 ± 1.5 | 11.3 ± 1.4 | 11.3 ± 1.5 | 0.96 |
| Albumin (g/dL) | 3.9 ± 0.5 | 3.9 ± 0.5 | 3.9 ± 0.5 | 0.87 |
| CRP (mg/L) | 5.0 (3.0–13.0) | 4.1 (2.9–12.0) | 5.7 (3.0–14.0) | 0.02 |
| Calcium (mg/dL) | 9.1 ± 0.9 | 9.2 ± 0.9 | 9.0 ± 0.9 | 0.001 |
| Phosphate (mg/dL) | 5.0 ± 1.6 | 5.2 ± 1.6 | 4.9 ± 1.6 | 0.001 |
∗Cardiovascular comorbidities: the presence, at baseline, of at least one of these comorbidities: angina, arrhythmia, myocardial infarction, coronary surgery, angioplasty, other heart surgeries, claudicatio intermittens, amputations, peripheral surgery, stroke, TIA, and preexisting chronic heart failure.
Data are expressed as mean ± SD or median and interquartile range or as percent frequency, as appropriate.