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. 2016 Jul 25;2016:2684321. doi: 10.1155/2016/2684321

Figure 6.

Figure 6

DH recruits more MDSCs to liver and inhibits the infiltration of macrophages in liver. Notes: hepatitis was induced by i.v. injection of ConA (15 mg/kg). Liver mononuclear cells were isolated from mice at 18 h following ConA injection. CD11b+ Gr1+ MDSCs (a) and CD45+ F4/80+ Kupffer cells (b) were stained and analyzed by flow cytometer. Numbers in quadrants indicate the percentage of cells in each ((a)(A) and (b)(A)). Proportions of CD11b+ Gr1+ MDSCs (a)(B) and CD45+ F4/80+ Kupffer cells (b)(B) among total liver mononuclear cell population (mean ± SD n = 3; ∗∗∗ P < 0.0001). ConA: Concanavalin A; DH: Dracocephalum heterophyllum; MDSCs: myeloid-derived suppressor cells.