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State-of-the-art interpretation of EBV-specific serological profiles for diagnoses
| Heterophile antibodies | Atypical lymphocytes | VCA IgG | VCA IgM | EBNA-1 IgG | Interpretation |
|---|---|---|---|---|---|
| ± | ± | + | + | − | Acute infection |
| − | − | + | − | + | Past infection |
| − | − | − | − | − | No infection |
| ± | ± | + | − | − | Indeterminatea |
| − | − | + | + | + | Indeterminatea |
| − | − | − | + | − | Indeterminatea |
| − | − | − | − | + | Not plausible |
Further testing needed, such as avidity testing of VCA IgG, Western blot analysis, or PCR.
