TABLE 3.
Estimated antibody prevalence rates early after clinical presentation in a single acute-phase serum sample from immunocompetent individuals with primary EBV infectionsa
Antigen(s) | Antibody class | Prevalence rate (%) | Methodc |
---|---|---|---|
Heterophile antibodies | IgM | 50-85b | Agglutination, rapid tests |
Viral capsid antigen | IgG | 98-100 | IFA, EIA, WBd |
Viral capsid antigen | IgM | 70-100 | IFA, EIA, WB |
Nuclear antigen 1 | IgG | 0 | IFA, EIA, WB |
Early antigen | IgG | 60-80 | IFA, EIA, WB |
Depending on the age of the patient.
Prevalence rates strongly depend on the method (IFA, EIA, or Western blot analysis) and on the different commercially available tests (manufacturer) used for determination.
WB, western blot analysis.