Table 1.

Percentage of Splenic Lymphoid Populations in the Three Treatment Groups of NOD-H2^h4 Mice, According to the Major Lymphoid Subpopulations

	Phosphate buffered saline (group C)	Control hamster immunoglobulins (group B)	Hamster anti-mouse CTLA-4 (group A)	p-Value comparing group A vs. B
Total splenocytes	5.34 ± 0.75	4.45 ± 0.73	6.01 ± 1.04	0.1675
CD3+ T cells	42.68 ± 5.81	43.45 ± 4.99	47.44 ± 3.36	0.082
CD4+ T cells	23.16 ± 4.31	24.4 ± 1.23	27.6 ± 1.15	<0.001
CD8+ T cells	19.48 ± 2.65	19.1 ± 2.43	19.9 ± 1.77	0.464
CD4/CD8 ratio	1.20 ± 0.24	1.29 ± 0.11	1.3 ± 0.17	0.890
CD4+CD69+ T cells	2.37 ± 0.16	2.62 ± 0.20	3.24 ± 0.22	<0.001
CD4+CD25+ T cells	2.78 ± 0.50	3.55 ± 0.33	5.16 ± 0.46	<0.001
DX5+ NK cells	0.91 ± 0.20	1.19 ± 0.09	0.95 ± 0.09	0.001
B220+ B cells	57.2 ± 2.68	59.5 ± 3.11	55.8 ± 4	0.058

For total spleen cells, numbers are expressed as absolute values.