Table 3. Genotypes and major allele frequencies of TLR7 rs179008 and TLR8 rs2407992 genes in 70 female patients in relation to clinical characteristics of bronchiolitis.
TLR7 females N = 70 | AA N = 43, No. (%) | AT N = 23, No. (%) | TT N = 4, No. (%) | Major allele AN = 109, No. (%) |
---|---|---|---|---|
Virus RSV N = 52 | 34 (79.1) p = 0.19 | 15 (65.2) | 3 (75.0) p = 0.73 | 83 (76.1) p = 0.71 |
Oxygen required N = 16 | 9 (20.9) p = 0.42 | 6 (26.1) | 1 (25.0) p = 0.67 | 24 (22.0) p = 0.73 |
Feeding support N = 28 | 19 (67.9) p = 0.26 | 7 (30.4) | 2 (50.0) p = 0.53 | 45 (41.3) p = 0.70 |
LOS, mean in days (standard deviation) | 5.4 (SD 3.7) p = 0.51 | 5.0 (SD 3.0) | 4.0 (SD 1.8) p = 0.48 | |
TLR8 females N = 70 | GG N = 19, No. (%) | GC N = 41, No. (%) | CC N = 10, No. (%) | Major allele G N = 79, No. (%) |
Virus RSV N = 52 | 14 (73.7) p = 0.59 | 30 (73.2) | 8 (80.0) p = 0.50 | 58 (73.4) p = 0.92 |
Oxygen required N = 16 | 5 (26.3) p = 0.45 | 10 (24.4) | 1 (10.0) p = 0.28 | 20 (25.3) p = 0.56 |
Feeding support N = 28 | 9 (47.4) p = 0.31 | 15 (36.4) | 4 (40.0) p = 0.64 | 33 (41.8) p = 0.75 |
LOS, mean in days (standard deviation) | 4.9 (SD 2.1) p = 0.69 | 5.4 (SD 3.9) | 4.8 (SD 3.4) p = 0.72 |
The length of hospital stay (LOS) was mean 5.2 days (SD 3.4, range 1–25) in all 70 cases. Major allele vs minor allele.