Table 5. Genotypes and major allele frequencies of TLR9 rs187084 (N = 133) and TLR10 rs4219009 (N = 135) genes in bronchiolitis patients in relation to the clinical characteristics of bronchiolitis.
TLR9 N = 133 | TT N = 42, No. (%) | CT N = 55, No. (%) | CC N = 36, No. (%) | Major allele T N = 139, No. (%) |
---|---|---|---|---|
Virus RSV N = 99 | 33 (78.6) p = 0.78 | 39 (70.9) | 27 (75.0) p = 0.97 | 105 (75.5) p = 0.87 |
Oxygen required N = 25 | 7 (16.7) p = 0.43 | 13 (23.6) | 5 (13.9) p = 0.27 | 27 (19.4) p = 0.82 |
Feeding support N = 45 | 14 (33.3) p = 0.55 | 21 (38.9) | 10 (27.8) p = 0.25 | 49 (35.3) p = 0.72 |
LOS, mean in days (standard deviation) | 5.10 (SD 3.80) p = 0.85 | 4.45 (SD 2.41) | 4.61 (SD 3.58) p = 0.34 | |
TLR10 N = 135 | AA N = 113, No. (%) | AG N = 21, No. (%) | GG N = 1, | Major allele A N = 247, No. (%) |
Virus RSV N = 101 | 84 (74.3) p = 0.50 | 16 (76.2) | 1 | 184 (74.5) p = 0. |
Oxygen required N = 25 | 22 (19.5) p = 0.38 | 2 (9.5) | 1 | 46 (18.6) p = 0. |
Feeding support N = 47 | 40 (35.4) p = 0.48 | 6 (28.6) | 1 | 86 (34.8) p = 0. |
LOS, mean in days (standard deviation) | 4.74 SD 3.25 p = 0.94 | 4.52 SD 3.04 | NC |
The length of hospital stay (LOS) was mean 4.7 days (SD 3.2, range 0–22) in all 133 cases.
NC not calculated. Major allele vs minor allele.