Table 1. Targeting sites chosen for Cas9-HR and oligonucleotides used to generate the corresponding gRNAs.

Guide sequence insert 1 Forward	5′CAACCGATTATTTGGAGACTATGGAAGG 3′
Guide sequence insert 1 Reverse	5′AAACCCTTCCATAGTCTCCAAATAATC 3′
Guide sequence insert 2 Forward	5′ CACCCCACTCTAGTACTATATCTGTCA 3′
Guide sequence insert 2 Reverse	5′AAACTGACAGATATAGTACTAGAGTGG 3′