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. 2016 Aug 8;6:30997. doi: 10.1038/srep30997

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) PCoA was performed to analyse rc-rRNA and mRNA abundances, and 12 samples in both the peri-implantitis and periodontitis groups are plotted with two coordinates. The mean and standard deviation in each axis are indicated by an ellipse. Dots corresponding to rc-rRNA and mRNA in the same patient are connected by a broken line. (B) VTiFs shown in MA plots for peri-implantitis and periodontitis samples. The y axis shows difference values [M] of rc-rRNA and mRNA abundances and the x axis shows mean values [A]. Coloured points indicate taxa with statistically significant differences in abundance between rc-rRNAs and mRNAs. (C) mRNA/rc-rRNA abundance ratio calculated for each VTiF shown in (B); predominant taxa (based on mean log2 ratios) for the 12 samples are shown in descending order.