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. 2016 Aug 8;6:30976. doi: 10.1038/srep30976

Figure 3. miR-939 reduced the translocation of functional NFκB to nucleus in response to LPS stimulation.

Figure 3

HUVEC cells were transfected with miR-939 for 24 h, followed by LPS stimulation for 6 h and fixed. Immunostaining was performed with anti-NFκB antibody (green), Actin (red) and DAPI (blue). While LPS stimulation of HUVEC cells results in the translocation of NFκB to the nucleus (C) in comparison to untreated control (A), this is impaired in cells transfected with miR-939 (D), suggesting that a potential regulation of NFκB2 subunit by miR-939 can influence the dimerization and function of NFκB.