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. 2016 Aug 8;6:30941. doi: 10.1038/srep30941

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Bladder cancer cells (T24) were subcutaneously transplanted into nude mice. Control or SLD5-specific siRNA was injected on day10 post-inoculation. (A) Time course of tumor volume dynamics. Data are mean ± SE (n = 3). (B) Tumor weight on day 30 post-inoculation. *p < 0.05 mean ± SE. (C) qRT-PCR analysis for assessment of SLD5 mRNA expression in control and SLD5 siRNA-injected tumors. Data are mean ± SE ***p < 0.0001. (D) Xenograft tumors injected with control or SLD5 siRNA were stained with anti-SLD5 or Ki-67 antibody (brown). Sections were counterstained with hematoxylin. Scale bars: 100 μm.