Table 2. Ovarian stimulation characteristics and outcomes.
| Characteristic | P (ng/mL) | P Value | |||
|---|---|---|---|---|---|
| <1 (n = 3376) | 1–1.5 (n = 531) | 1.5–2 (n = 120) | ≥2 (n = 79) | ||
| Total hMG dose (IU),mean (95%CI) | 1931.95(1917.05–1946.85) | 2069.52(2032.12–2106.92) | 2100.00(2041.20–2158.80) | 2081.49(2011.84–2151.14) | <0.001a |
| Duration of stimulation (d), mean (95%CI) | 8.92(8.86–8.92) | 9.35(9.22–9.48) | 9.51(9.28–9.74) | 9.57(9.31–9.84) | <0.001a |
| Number of oocyte aspirated. mean (95%CI) | 15.14(14.82–15.46) | 25.62(24.58–26.66) | 30.61(28.26–32.96) | 30.74(27.57–33.91) | <0.001a |
| Number of oocyte retrieved, mean (95%CI) | 10.38(10.15–10.60) | 17.99(17.25–18.73) | 20.39(18.85–21.94) | 19.84(17.59–22.10) | <0.001a |
| Oocyte retrieval rate, mean (95%CI) | 70.45(69.74–71.16) | 72.01(70.45–73.57) | 68.79(65.42–72.17) | 66.89(62.47–70.93) | NS |
| Normal fertilization rate, mean (95%CI) | 89.79(89.18–90.39) | 90.00(88.88–91.13) | 88.93(86.37–91.49) | 89.38(85.43–93.33) | NS |
| Embryos frozen, mean (95%CI) | 4.15(4.06–4.24) | 5.97(5.69–6.26) | 6.61(5.90–7.32) | 6.43(5.55–7.31) | <0.001a |
| Top-quality embryos, mean (95%CI) | 2.33(2.21–2.45) | 2.87(2.59–3.22) | 2.44(1.96–2.93) | 3.08(2.03–4.13) | <0.05b |
| Hormones on day of trigger | |||||
| FSH (mIU/mL), mean (95%CI) | 15.03(14.89–15.17) | 16.59(16.24–16.95) | 16.15(15.48–16.81) | 16.35(16.12–17.29) | <0.001a |
| LH (mIU/mL), mean (95%CI) | 1.74(1.69–1.80) | 1.78(1.66–1.90) | 2.10(1.65–2.55) | 3.98(1.29–6.67) | <0.001b |
| E2 (pg/mL), mean (95%CI) | 2844.63(2794.82–2894.44) | 4492.73(4387.56–4597.90) | 4838.66(4728.63–4948.68) | 4412.58(4141.50–4683.67) | <0.001a |
Data are presented as the means and 95% confidence interval.
aIndicates group with P < 1 ng/mL versus groups with P between 1–1.5 ng/mL, P between 1.5–2 ng/mL and P ≥ 2 ng/mL.
bIndicates group with P < 1 ng/mL versus group with P ≥ 2 ng/mL.