Table 1.
Patient characteristics
| All patients Mean ± SD or n (%) |
No PH Mean ± SD or n (%) |
PH Mean ±SD or n (%) |
P (T-test / Fisher’s exact test)^ |
|
|---|---|---|---|---|
| N | 235 | 116 (49.4) | 119 (50.6) | |
| Age (year) | 59.3 ± 8.9 | 60.7 ± 8.5 | 57.9 ± 9.1 | 0.02 |
| Male gender | 167 (71.1) | 79 (68.1) | 88 (73.9) | 0.32 |
| Lung allocation score29 | 49.3 ± 18.8 | 44.1 ± 15.2 | 54.0 ± 20.4 | <0.001 |
| Hemodynamic data | ||||
| -Systolic ABP (mm Hg) | 129.4 ± 19.0 | 131.1 ± 20.0 | 128.4 ± 18.7 | 0.67 |
| -Diastolic ABP (mm Hg) | 83.9 ± 17.2 | 83.4 ± 9.9 | 84.2 ± 20.7 | 0.89 |
| -RA pressure (mm Hg) | 6.2 ± 4.3 | 4.4 ± 2.7 | 7.9 ± 4.6 | <0.001 |
| -Systolic PAP (mm Hg) | 43.8 ± 16.8 | 32.6 ± 6.8 | 54.8 ± 16.4 | <0.001 |
| -Diastolic PAP (mm Hg) | 17.9 ± 8.6 | 12.6 ± 4.7 | 23.1 ± 8.4 | <0.001 |
| -Mean PAP (mm Hg) | 27.1 ± 10.8 | 19.2 ± 4.0 | 34.7 ± 9.7 | <0.001 |
| -PAWP (mm Hg) | 10.7 ± 6.0 | 8.6 ± 4.4 | 12.8 ± 6.6 | <0.001 |
| -CO (L/min) | 5.4 ± 1.5 | 5.3 ± 1.4 | 5.5 ± 1.6 | 0.33 |
| -CI (L/min/m2) | 2.8 ± 0.7 | 2.9 ± 0.7 | 2.8 ± 0.7 | 0.44 |
| -PVR (Wood Units) | 3.4 ± 2.4 | 2.2 ± 1.1 | 4.6 ± 2.8 | <0.001 |
| Echocardiographic data | ||||
| Left ventricular EF (%) | 56.4 ± 10.5 | 56.8 ± 6.3 | 57.5 ± 6.5 | 0.93 |
| RVSP (mmHg)* | 49.1 ± 20.4 | 43.8 ± 15.0 | 54.1 ±23.5 | 0.001 |
| TAPSE (cm)¶ | 1.4 ± 0.4 | 1.40 ± 0.4 | 1.3 ± 0.4 | 0.31 |
| RV diameter (cm)‡ | ||||
| -Basal | 4.1 ± 0.8 | 3.9 ± 0.7 | 4.2 ± 0.8 | 0.01 |
| -Mid | 3.7 ± 0.8 | 3.5 ± 0.7 | 3.8 ± 0.9 | 0.02 |
| -Longitudinal | 7.0 ± 1.1 | 6.8 ± 1.1 | 7.1 ± 1.1 | 0.04 |
| RV dysfunction | ||||
| -Not available | 50 (21.3) | |||
| -Normal | 111 (47.2) | 66 (75.0) | 45 (46.4) | |
| -Mild | 34 (14.5) | 13 (14.8) | 21 (21.6) | <0.001 |
| -Moderate | 18 (7.7) | 6 (6.8) | 12 (12.4) | |
| -Severe | 22 (9.4) | 3 (3.4) | 19 (19.6) | |
Abbreviations: ABP: arterial blood pressure, CI: cardiac index, CO: cardiac output, EF: ejection fraction, PAWP: pulmonary artery wedge pressure, PAP: pulmonary artery pressure, PVR: pulmonary vascular resistance, RA: right atrium, RV: right ventricle, RVSP: right ventricular systolic pressure, TAPSE: tricuspid annular plane systolic excursion.
*
Data available in 159 patients.
¶
Data available in 166 patients.
‡
Data available in 159 patients.
^
p values are given for reference only and have not been adjusted for multiple comparison.