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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Respir Med. 2016 Jun 2;117:65–72. doi: 10.1016/j.rmed.2016.06.001

Table 5.

Univariable analysis to predict patients with precapillary PH (PVR > 3 Wood Units)

Variables (incremental change) OR 95%CI p C-index 95%CI
PaO2 (every 10 mmHg) 0.62 0.47–0.82 0.001 0.32 0.24–0.40
SaO2 (every 10 %) 0.39 0.25–0.62 <0.001 0.30 0.21–0.38
TLC (every 10 %) 1.32 1.06–1.67 0.02 0.58 0.49–0.68
DLCOc (every 10 %) 0.52 0.35–0.78 0.001 0.34 0.25–0.43
FVC/DLCOc (every 0.1) 2.20 1.47–3.32 <0.001 0.69 0.59–0.78
PA diameter (every 1 cm) 2.84 1.50–5.40 0.001 0.65 0.56–0.74
PA/AA diameter ratio (every 0.1) 1.60 1.27–2.00 <0.001 0.69 0.60–0.77
6MWD (every 10 m) 0.96 0.92–0.99 0.006 0.38 0.29–0.46
6MWD %predicted (every 10
%)
0.70 0.57–0.87 0.001 0.31 0.21–0.41
P axis (every 10 degrees) 1.22 1.03–1.44 0.02 0.60 0.51–0.68
P wave in lead II (every 0.1 mV) 2.26 1.35–3.79 0.002 0.65 0.57–0.73
QRS axis (every 10 degrees) 1.21 1.12–1.30 <0.001 0.69 0.61–0.77
T axis (every 10 degrees) 0.90 0.82–1.00 0.04 0.40 0.32–0.49
V1–V3 ST depression (Yes) 3.60 1.58–8.21 0.002
IRBBB (Yes) 4.19 1.95–9.03 <0.001
RVSP (every 10 mmHg) 1.46 1.21–1.76 <0.001 0.68 0.58–0.78
RV dilation (every 1 grade^) 2.39 1.59–3.61 <0.001
RV function (every 1 grade^) 2.85 1.92–4.23 <0.001
RV basal diameter (per 1 cm) 1.68 1.08–2.60 0.02 0.61 0.52–0.71
RV mid diameter (per 1 cm) 1.81 1.18–2.78 0.007 0.62 0.52–0.72

Abbreviations: 6MWD: distance walked in six minute walk test, AA: ascending aorta, DLCOc: corrected diffusion lung capacity of carbon monoxide, IRBBB: incomplete right bundle branch block, PA: pulmonary artery, PaO2: pulmonary artery pressure of O2, PVR: pulmonary vascular resistance, RV: right ventricle, RVSP: right ventricular systolic pressure, SaO2: arterial O2 saturation, TLC: total lung capacity.

^

a change from normal to mild, mild to moderate or moderate to severe.