Table 5.
Univariable analysis to predict patients with precapillary PH (PVR > 3 Wood Units)
Variables (incremental change) | OR | 95%CI | p | C-index | 95%CI |
---|---|---|---|---|---|
PaO2 (every 10 mmHg) | 0.62 | 0.47–0.82 | 0.001 | 0.32 | 0.24–0.40 |
SaO2 (every 10 %) | 0.39 | 0.25–0.62 | <0.001 | 0.30 | 0.21–0.38 |
TLC (every 10 %) | 1.32 | 1.06–1.67 | 0.02 | 0.58 | 0.49–0.68 |
DLCOc (every 10 %) | 0.52 | 0.35–0.78 | 0.001 | 0.34 | 0.25–0.43 |
FVC/DLCOc (every 0.1) | 2.20 | 1.47–3.32 | <0.001 | 0.69 | 0.59–0.78 |
PA diameter (every 1 cm) | 2.84 | 1.50–5.40 | 0.001 | 0.65 | 0.56–0.74 |
PA/AA diameter ratio (every 0.1) | 1.60 | 1.27–2.00 | <0.001 | 0.69 | 0.60–0.77 |
6MWD (every 10 m) | 0.96 | 0.92–0.99 | 0.006 | 0.38 | 0.29–0.46 |
6MWD %predicted (every 10 %) |
0.70 | 0.57–0.87 | 0.001 | 0.31 | 0.21–0.41 |
P axis (every 10 degrees) | 1.22 | 1.03–1.44 | 0.02 | 0.60 | 0.51–0.68 |
P wave in lead II (every 0.1 mV) | 2.26 | 1.35–3.79 | 0.002 | 0.65 | 0.57–0.73 |
QRS axis (every 10 degrees) | 1.21 | 1.12–1.30 | <0.001 | 0.69 | 0.61–0.77 |
T axis (every 10 degrees) | 0.90 | 0.82–1.00 | 0.04 | 0.40 | 0.32–0.49 |
V1–V3 ST depression (Yes) | 3.60 | 1.58–8.21 | 0.002 | ||
IRBBB (Yes) | 4.19 | 1.95–9.03 | <0.001 | ||
RVSP (every 10 mmHg) | 1.46 | 1.21–1.76 | <0.001 | 0.68 | 0.58–0.78 |
RV dilation (every 1 grade^) | 2.39 | 1.59–3.61 | <0.001 | ||
RV function (every 1 grade^) | 2.85 | 1.92–4.23 | <0.001 | ||
RV basal diameter (per 1 cm) | 1.68 | 1.08–2.60 | 0.02 | 0.61 | 0.52–0.71 |
RV mid diameter (per 1 cm) | 1.81 | 1.18–2.78 | 0.007 | 0.62 | 0.52–0.72 |
Abbreviations: 6MWD: distance walked in six minute walk test, AA: ascending aorta, DLCOc: corrected diffusion lung capacity of carbon monoxide, IRBBB: incomplete right bundle branch block, PA: pulmonary artery, PaO2: pulmonary artery pressure of O2, PVR: pulmonary vascular resistance, RV: right ventricle, RVSP: right ventricular systolic pressure, SaO2: arterial O2 saturation, TLC: total lung capacity.
a change from normal to mild, mild to moderate or moderate to severe.