Table 1.
Clinical Trial–Related Activities 5 Years Before and During NCCCP at SFCTC
| Activity | 5 Years Before NCCCP, July 2002 to June 2007 | 5 Years of NCCCP, July 2007 to June 2012 | P | First Year of NCORP, July 2014 to June 2015 |
|---|---|---|---|---|
| No. of dedicated clinical trial staffing (FTE) | 2 (1.2) | 5 (3.9) | .012 | 6 (5) |
| Total No. of accruals (range) | 83 (9-35) | 640 (51-230) | 90 | |
| Overall participation rate in trials, % (range) | 3.2 (2-7) | 23 (9-41) | < .001 | 18 |
| Average accrual No. per clinical trial | 13.2 | 15.8 | .5 | 1.61 |
| No. of clinical trials by sponsor (range) | ||||
| Cooperative | 46 (5-14) | 130 (14-29) | 43 | |
| Industry | 3 (1-2) | 48 (3-15) | 5 | |
| Investigator initiated | 5 (0-1) | 33 (2-10) | 8 | |
| Total | 54 (6-17) | 211 (19-54) | 56 | |
| No. of clinical trials by type (range) | ||||
| Total treatment | 40 (4-14) | 138 (14-36) | .015 | 46 |
| Average No. per year | 8 | 28 | NA | |
| Total nontreatment | 15 (0-10) | 61 (3-33) | .009 | 10 |
| Average No. per year | 3 | 12 | NA | |
| Supportive care | 0 | 10 (0-10) | ||
| Prevention | 0 | 3 (0-1) | 0 | |
| Quality of life | 4 (0-1) | 8 (1-2) | 0 | |
| Cancer care delivery | 0 | 7 (1-2) | 2 | |
| Biospecimen | 10 (2-5) | 33 (3-9) | 1 | |
| Annual rate of increase in: | ||||
| No. of available trials | 3.4 | 6.7 | .36 | NA |
| No. of accruals | 3.1 | 36.9 | .02 | NA |
| Percentage of accruals | 0.6 | 6.5 | .03 | NA |
Abbreviations: FTE, full-time equivalent; NA, not applicable; NCCCP, National Cancer Institute Community Cancer Centers Program; NCORP, National Cancer Institute Community Oncology Research Program; SFCTC, Saint Francis Cancer Treatment Center.