Table 2.
The sensitivity and specificity of “sandwich” and “target” signs for collagen VI-related myopathies and other neuromuscular disorders (disease controls)
| Signs | Collagen VI myopathies (n = 11) | Disease controls (n = 361) | Sensitivity, % | Specificity, % | Disease controls with the signs | |||
|---|---|---|---|---|---|---|---|---|
| Dystrophinopathies (n = 166) | LGMD2B (n = 33) | LGMD2A (n = 15) | LMNA-related myopathy (n = 8) | |||||
| Sandwich | 90.9 | 96.1 | ||||||
| Positive | 10 | 14 | 4 | 4 | 4 | 2 | ||
| Negative | 1 | 347 | 162 | 29 | 11 | 6 | ||
| Target | 63.6 | 97.0 | ||||||
| Positive | 7 | 11 | 7 | 2 | 1 | 1 | ||
| Negative | 4 | 350 | 159 | 31 | 14 | 7 | ||
LGMD2B: Limb-girdle muscular dystrophy 2B; LGMD2A: Limb-girdle muscular dystrophy 2A.