Table 3.
4 weeks (midway) | 8 weeks (end) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline BP | Mean BP | BP change | Difference from control (95% CI) | p | Mean BP | BP change | Difference from control (95% CI) | p | ||
Systolic BP | ||||||||||
Hypertensive | Control | 152.7 (3.1) | 141.8 (3.3) | −10.9 (2.2) | 139.1 (2.9) | −13.7 (2.5) | ||||
Gamalost® | 150.8 (4.4) | 144.2 (4.6) | −6.7 (2.8) | 4.3 (−4.3, 12.9) | 0.43 | 141.3 (3.9) | −9.50 (2.5) | 4.2 (−3.4, 11.8) | 0.36 | |
Gouda-type | 151.5 (2.6) | 147.9 (3.5) | −0.4 (3.7) | 10.5 (0.9, 20.2) | 0.03 | 147.9 (3.5) | −3.6 (2.1) | 10.1 (1.6, 18.6) | 0.02 | |
Normal-high | Control | 129.2 (2.1) | 129.7 (2.1) | 0.3 (1.7) | 128.7 (1.9) | −0.6 (1.7) | ||||
Gamalost® | 128.4 (1.4) | 124.4 (2.2) | −4.1 (1.7) | −4.3 (−9.8, 1.1) | 0.14 | 125.4 (1.9) | −3.0 (1.7) | −2.4 (−8.1, 3.4) | 0.55 | |
Gouda-type | 128.6 (1.0) | 127.9 (1.6) | −0.5 (1.5) | −0.8 (−6.0, 4.3) | 0.91 | 124.9 (2.1) | −3.5 (1.7) | −2.9 (−8.3, 2.5) | 0.37 | |
Optimal | Control | 111.5 (1.4) | 114.9 (2.8) | 3.4 (2.4) | 111.8 (2.6) | 0.3 (2.2) | ||||
Gamalost® | 112.5 (1.3) | 112.3 (2.5) | −0.1 (1.9) | −3.5 (−11.7, 4.7) | 0.50 | 113.5 (2.0) | 0.5 (1.6) | 0.2 (−6.8, 6.4) | 1.0 | |
Gouda-type | 112.9 (1.3) | 127.9 (1.6) | −0.4 (3.1) | −3.8 (−12.5, 5.0) | 0.50 | 109.7 (2.3) | −3.5 (1.9) | −3.8 (−10.2, 2.7) | 0.31 | |
Diastolic BP | ||||||||||
Hypertensive | Control | 91.9 (2.2) | 141.8 (3.3) | −5.1 (2.0) | 88.5 (2.3) | −3.4 (2.1) | ||||
Gamalost® | 92.2 (2.6) | 144.2 (4.6) | −4.1 (1.4) | 1.0 (−4.5, 6.5) | 0.89 | 87.6 (2.6) | −4.6 (1.4) | −1.2 (−6.8, 4.4) | 0.85 | |
Gouda-type | 92.0 (2.3) | 147.9 (3.5) | −0.9 (2.1) | 4.1 (−2.0, 10.3) | 0.23 | 92.3 (2.5) | −0.8 (1.8) | 2.6 (−3.6, 8.9) | 0.54 | |
Normal-high | Control | 80.8 (1.0) | 80.5 (1.6) | −0.1 (1.3) | 80.6 (1.5) | 0.1 (1.5) | ||||
Gamalost® | 81.0 (1.2) | 77.5 (1.1) | −3.6 (1.1) | −3.5 (−7.3, 0.4) | 0.08 | 78.8 (1.3) | −2.2 (1.0) | −2.2 (−6.4, 2.1) | 0.42 | |
Gouda-type | 80.9 (0.8) | 79.3 (1.1) | −1.4 (1.0) | −1.3 (−4.9, 2.4) | 0.65 | 79.7 (1.3) | −0.9 (1.3) | −0.9 (−4.9, 3.1) | 0.84 | |
Optimal | Control | 70.5 (1.2) | 68.5 (1.2) | −2.0 (1.3) | 71.8 (2.4) | 1.3 (1.8) | ||||
Gamalost® | 73.0 (1.0) | 69.7 (1.9) | −3.7 (1.7) | −1.7 (−7.7, 4.3) | 0.72 | 71.9 (1.4) | −1.5 (1.5) | −2.8 (−8.0, 2.4) | 0.36 | |
Gouda-type | 71.3 (1.5) | 79.3 (1.1) | 1.3 (2.0) | 3.3 (−3.1, 9.7) | 0.38 | 71.2 (1.1) | −0.8 (1.3) | −2.1 (−7.5, 3.4) | 0.59 |
Values are mean (SE), 2-sided p-values for the difference from control (Dunnett test).