FIG. 5.
The principle of stochastic optical reconstruction microscopy (STORM). A target structure (A) is activated by a subset of probes (B). In (B), green circles that do not overlap are the activated images of fluorescent labels at any given time. Red crosses are the activated fluorophore positions. (C) After enough fluorophores have been localized, a high-resolution image is constructed by plotting the measured positions. (Reprinted by permission from Nature Publishing Groups. Copyright © 2009 Nature Photonics.)