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. 2015 Oct 19;36(8):1374–1383. doi: 10.1177/0271678X15610786

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© The Author(s) 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — miR-122 (2.4mg/kg i.v.) mimic maintains vessel caliber, vWF immunoreactivity, and prevents ICAM-1 induction one day after MCAO in rats compared to scramble miRNA. Scrambled miRNA mimic and miR-122 mimic were wrapped using PEG-liposomes prior to i.v. administration after MCAO. Note induction of ICAM1 with scramble miRNA (E) which is blocked by miR-122 mimic (H). Note decrease in vessel caliber following scramble miRNA (D) which is prevented by miR-122 mimic (G). n = 4/group. Scale bars: A–I, 50 µm.