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. 2015 Oct 13;36(8):1412–1423. doi: 10.1177/0271678X15606459

Figure 7.

Figure 7.

Plasma concentrations of risperidone (a) and its metabolite (paliperidone) (b) in WT mice (black circles) and R6/2 HD mice (white circles) after an intravenous injection of 3 mg/kg risperidone. The asterisk indicates P < 0.05 compared to HD mice. (c) Plasma concentrations of paliperidone after an intravenous injection of 3 mg/kg paliperidone. (d) Brain-to-plasma ratios of risperidone or paliperidone after an intravenous injection of 3 mg/kg risperidone or paliperidone, respectively. The data are presented as the mean ± SEM of five mice.