Group average aBVDia, aBVSys and AC plotted against slice location from two slices below to three slices above the CoW. On the right, an example of the slice locations is overlaid on an angiogram for a single subject. Note that the data are averaged over the ROIs of the major brain feeding arteries below the Circle of Willis (internal carotid and basilar/vertebral arteries) and both RMCA and LMCA above the CoW. Although none of the ROIs show a change in aBVDia, the larger and more proximal arteries show a decrease in aBVSys during PEI. Note that this leads to the figure on the right, where it can be seen that the arteries below and at the level of the CoW show a decrease in AC during PEI, while the MCAs more distal from the CoW show no decrease in AC during PEI. Error bars indicate SEM. AC: Arterial compliance; PEI: Post exercise ischemia; CoW: Circle of Willis.