Table 2.

Acceptance and rejection numbers used for trial design, $(r_1^{\ast }\left(j\right),r_2^{\ast }\left(j\right))$ for the test statistics given in Equations 4 and 6.

	ε1 = 0.20, ε2 = 0.20	ε1 = 0.20, ε2 = 0.20
	q0 = 0.05, q1 = 0.30	q0 = 0.15, q1 = 0.30
	$r_1^{\ast }\left(j\right),r_2^{\ast }\left(j\right)$	$r_1^{\ast }\left(j\right),r_2^{\ast }\left(j\right)$
Patient No.	for T1 for T3	for T1 for T3
1	( - , - ) ( - , 1 )	( - , - ) ( - , - )
2	( - , - ) ( - , 1 )	( - , 2 ) ( - , 2 )
3	( - , 2 ) ( - , 2 )	( - , 2 ) ( - , 3 )
4	( - , 2 ) ( - , 2 )	( - , 2 ) ( - , 3 )
5	( - , 2 ) ( 0 , 2 )	( - , 3 ) ( - , 3 )
6	( - , 2 ) ( 0 , 2 )	( 1 , 3 ) ( - , 3 )
7	( - , 2 ) ( 0 , 2 )	( 1 , 3 ) ( - , 4 )
8	( 1 , 2 ) ( 0 , 2 )	( 1 , 3 ) ( 0 , 4 )
9	( 1 , 3 ) ( 0 , 2 )	( 1 , 4 ) ( 0 , 4 )
10	( 1 , 3 ) ( 0 , 3 )	( 1 , 4 ) ( 0 , 4 )
11	( 1 , 3 ) ( 0 , 3 )	( 2 , 4 ) ( 0 , 4 )
12	( 1 , 3 ) ( 1 , 3 )	( 2 , 4 ) ( 1 , 5 )
13	( 1 , 3 ) ( 1 , 3 )	( 2 , 5 ) ( 1 , 5 )
14	( 1 , 3 ) ( 1 , 3 )	( 2 , 5 ) ( 1 , 5 )
15	( 2 , 4 ) ( 1 , 3 )	( 2 , 5 ) ( 1 , 5 )
16	( 2 , 4 ) ( 1 , 3 )	( 3 , 5 ) ( 1 , 6 )
17	( 2 , 4 ) ( 1 , 4 )	( 3 , 6 ) ( 2 , 6 )
18	( 2 , 4 ) ( 1 , 4 )	( 3 , 6 ) ( 2 , 6 )
19	( 2 , 4 ) ( 2 , 4 )	( 3 , 6 ) ( 2 , 6 )
20	( 2 , 4 ) ( 2 , 4 )	( 3 , 6 ) ( 2 , 6)