Figure 2. . Alignment of the two highly conserved catalytic sites of 11 membrane-bound O-acyltransferase enzymes in human.

The highly conserved histidine residues and asparagine residues are highlighted in red and in yellow, respectively. The residues highlighted in gray are conserved in more than 50% of the all membrane-bound O-acyltransferases. Membrane-bound O-acyltransferases can be classified into three groups based on biochemical reactions they catalyze.

Reproduced with permission from [23] © Springer (2011).