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. 2016 Aug 8;11(8):e0160341. doi: 10.1371/journal.pone.0160341

Fig 4. ADCC activity of study samples.

Fig 4

ADCC activity was measured using purified IgG fractions against HIV-1SF162 (A) and HIV-1JR-FL (B) infected cells. Additionally, antibodies were evaluated against a clade A BG505 SOSIP.664 gp140 trimer coated cells (C). RM ANOVA and Dunnett’s multiple comparisons test revealed significantly enhanced ADCC activity only in the non-vaccine arm at weeks 36 (p = 0.03), compared to baseline (B). A significant decrease (p = 0.02) in ADCC activity was observed with the BG505 SOSIP.664 gp140 trimer coated cells in the non-vaccine group (C).