Fig 5. Correlation between virus neutralization and antibody signal intensities as well as ELISA antibody titers.

Median cross clade signal intensities and ELISA antibody titers were bifurcated into two specific groups (< median and > median) and compared to neutralization titers. Mann-Whitney test exhibited significantly lower HIV-1_SF162 IC50’s in subjects with higher microarray antibody signals (p = 0.0003) (A) or higher ELISA titers (p = 0.0094) (B). No differences were observed between HIV-1_JR-FL and antibody signals (C) or ELISA titers (D).