TABLE 2.

Comparison of performance characteristics of preharvest peripheral blood XN-HPC and CD34 analysis at selected cutoff points to predict successful apheresis meeting target CD34+ cell collections (≥2 × 10⁶/kg)

Donor type	Number	Cutoff (×106/L for XN-HPCs and CD34 cells	XN-HPC		CD34
			PPV (%)	NPV (%)	PPV (%)	NPV (%)
All	107	38*	71.4	97.7	78.9	98.0
Autologous	99		68.4	100	76.5	100
Allogeneic	8		100	50	100	50
All	107	20†	55.4	100	63.0	100
Autologous	99		52.0	100	59.1	100
Allogeneic	8		87.5	‡	100	100
All	107	15	50.0	100	57.5	100
Autologous	99		46.4	100	54.2	100
Allogeneic	8		87.5	‡	87.5	‡
All	107	10	45.1	100	51.7	100
Autologous	99		41.5	100	48.1	100
Allogeneic	8		87.5	‡	87.5	‡
All	107	5	44.2	100	44.2	100
Autologous	99		40.6	100	40.6	100
Allogeneic	8		87.5	‡	87.5	‡

^*Cutoff derived from ROC analysis.

^†Cutoff based on Armitage et al.¹⁴

^‡Unable to calculated NPV due to absence of true-negative population.