Figure 7. . Total histology scores received for each groups.

Joints retrieved 1 year post-implantation were stained with Hematoxylin & Eosin and Safranin-O and scored using a modified O'Driscoll score [30]. Histology scores were compiled by three co-authors based on parameters in Box 3. The maximum possible score is 28. Average scores are represented as means ± standard deviation. Gradient scaffold only group (n = 6), gradient scaffold + TGF-β3 group (n = 3), gradient scaffold + IGF group (n = 3) and microfracture group (n = 6). There were no statistically significant differences among the groups (p > 0.05).

LFC: Lateral femoral condyle; MFC: Medial femoral condyle.